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As additional longitudinal MRI data during multiyear intervals become available, future reports will examine examination validity of those findings. Finally, examination apparent slowing of AD true cortical thinning may not occur due to examination underlying biology but may be a outcome of examination technical issue of resolving thickness adjustments around and beyond exam voxel choice. Although our characterization of AD specific cortical thinning as a dynamic biomarker still may be valid, in examination attention of information examination underlying biology of this region, this talents confounder needs to be examined in future work. Funding/Support: Data collection and sharing for this task was funded by examination ADNI and NIH grant U01 AG024904 principal investigator , Dr Weiner. examination ADNI is funded by exam National Institute on Aging, by examination National Institute of Biomedical Imaging and Bioengineering, and through generous contributions from Abbott Laboratories, AstraZeneca AB, Bayer Schering Pharma AG, Bristol Myers Squibb, Eisai Global Clinical Development, Elan Corporation plc, Genentech Inc, GE Healthcare, GlaxoSmithKline plc, Innogenetics NV, Johnson and Johnson Services Inc, Eli Lilly and Company, Medpace Inc, Merck and Co Inc, Novartis International AG, Pfizer Inc, F. Hoffman La Roche Ltd, Schering Plough Corporation, SYNARC Inc, and Wyeth Pharmaceuticals, as well as nonprofit companions examination Alzheimer’s Association and exam Alzheimer’s Drug Discovery Foundation, with participation from examination US Food and Drug Administration.